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Ｒ392.12
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A
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:
1006-2084
(
2016
)
17-3356-04
doi
:
10.3969/j.issn.1006-2084.2016.17.008
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E-mail
:
drzhaodechao@163.com
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、
???ɼ?ֱ??ɱ????ʽ??ɱ??ԭ???Ĵ?ͳ?????????һ????????ʽ
———
??????ϸ??????״????
(
NETs
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NETs
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ＲesearchProgressofNeutrophilExtracellularTraps
HEJia-hui
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ZHONGJiao-yue
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LICai-ying
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ZHAO
De-chao．
(
DepartmentofCardiology
£¬
theFirstAffiliatedHospitalofHarbinMedicalUniversity
£¬
Harbin
150001
£¬
China
)
Abstract
:
Neutrophilsareimmunecellswhichareabundantinthehumanbodyplayingavitalrolein
hostimmunedefense
£¬
servingasthefirstlineofthehostdefenseagainstinfection．Thetraditionalcognitionof
neutrophilsismorefocusedonitsroleininnateimmunity．Ｒesearchfoundthatneutrophilsarecloselyassoci-
atedwithinflammatoryimmunitydefense．Andinrecentyearsneutrophilswerefoundtohaveanotherwayto
killpathogensinadditiontoitstraditionalmechanisms-neutrophilextracellulartraps
(
NETs
)
differentfrom
chemotaxis
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phagocytosisanddirectsterilizationmethods．SeveralstudieshaveconfirmedthatNETsplaya
dual-directionalregulationroleonthebody'simmunesystem．
Keywords
:
Neutrophil
;
Neutrophilextracellulartraps
;
Infection
;
Inflammatoryresponse
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2004
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Brinkmann
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1
中性粒细胞外网状陷阱的研究现状_赫嘉惠.pdf