【骨科指南】（英文版）2013+AAOS：膝关节骨关节炎循证医学指南.pdf

i TREATMENT OF OSTEOAR THRITIS OF THE KNEE EVIDENCE-BASED GUIDELINE 2 ND EDITION Adopted by the American Academy of Orthopaedic Surgeons Board of Directors May 18, 2013 ii Disclaimer This clinical practice guideline was developed by an AAOS work group comprised of volunteer physicians and interdisciplinary clinicians as well as staff researchers with expertise in systematic reviews and statistical methods used to evaluate empirical evidence. It is an educational tool that integrates the current scientific literature and the proficiency and sound judgment that physicians typically acquire in clinical practice. The recommendations that make up this guideline are not intended to be absolute as patients vary in how they experience symptoms and respond to treatment interventions. There may be variability between patients in practice and those who participate in clinical trials. Medical care should always be based on a physician’s expertise that is individually tailored to the patient’s circumstances, preferences and rights. Disclosure Requirement In accordance with AAOS policy, all individuals whose names appear as authors or contributors to this clinical practice guideline provided full disclosure of and were vetted for potential conflicts of interest prior to the introductory meeting. Funding Source The American Academy of Orthopaedic Surgeons funded this clinical practice guideline without any financial support from outside commercial sources. FDA Clearance Some drugs or medical devices referenced or described in this clinical practice guideline may not have been cleared by the Food and Drug Administration (FDA) or may have been cleared for a specific use only. The FDA has stated that it is the responsibility of the physician to determine the clearance status of each drug or device prescribed in clinical practice. Copyright All rights reserved. No part of this clinical practice guideline may be reproduced or sto