【骨科-指南】2015+IDSA临床实践指南：椎体骨髓炎的的诊断和管理.pdf

IDSA GUIDELINE 2015 Infectious Diseases Society of America (IDSA) Clinical Practice Guidelines for the Diagnosis and Treatment of Native Vertebral Osteomyelitis in Adults a Elie F. Berbari, 1 Souha S. Kanj, 2 Todd J. Kowalski, 3 Rabih O. Darouiche, 4 Andreas F. Widmer, 5 Steven K. Schmitt, 6 Edward F. Hendershot, 7 Paul D. Holtom, 8 Paul M. Huddleston III, 9 Gregory W. Petermann, 10 and Douglas R. Osmon 11 1 Division of Infectious Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota; 2 Division of Infectious Diseases, American University of Beirut Medical Center, Lebanon; 3 Division of Infectious Diseases, Gundersen Health System, La Crosse, Wisconsin; 4 Section of Infectious Diseases and Center for Prostheses Infection, Baylor College of Medicine, Houston, Texas; 5 Division of Infectious Diseases, Hospital of Epidemiology, University Hospital Basel, Switzerland; 6 Department of Infectious Disease, Cleveland Clinic, Ohio; 7 Department of Infectious Diseases, Duke University, Durham, North Carolina; 8 Department of Internal Medicine, University of Southern California, Los Angeles; 9 Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota; 10 Division of Spine Radiology, Marshfield Clinic, Wisconsin; and 11 Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota These guidelines are intended for use by infectious disease specialists, orthopedic surgeons, neurosurgeons, ra- diologists, and other healthcare professionals who care for patients with native vertebral osteomyelitis (NVO). They include evidence and opinion-based recommendations for the diagnosis and management of patients with NVO treated with antimicrobial therapy, with or without surgical intervention. Keywords.spondylodiscitis; osteomyelitis;Staphylococcus aureus EXECUTIVE SUMMARY Native vertebral osteomyelitis (NVO) in adults is often the result of hematogenous seeding of the adjacent disc space from a distant focus, as the disc is avascular [1,2]. The diagnosis of NVO ca