CE: Swati; JH-D-16-00542; Total nos of Pages: 34;
JH-D-16-00542
2016EuropeanSocietyofHypertensionguidelinesfor
themanagementofhighbloodpressureinchildren
andadolescents
Empar Lurbe
a,b
, Enrico Agabiti-Rosei
c
, J. Kennedy Cruickshank
d
, Anna Dominiczak
e
, Serap Erdine
f
,
Asle Hirth
g
, Cecilia Invitti
h
, Mieczyslaw Litwin
i
, Giuseppe Mancia
j
, Denes Pall
k
, Wolfgang Rascher
l
,
Josep Redon
b,m,n
, Franz Schaefer
o
, Tomas Seeman
p
, Manish Sinha
q
, Stella Stabouli
r
,
Nicholas J. Webb
s
, Elke Wu¨hl
t
, and Alberto Zanchetti
u
Increasing prevalence of hypertension (HTN) in children
and adolescents has become a significant public health
issue driving a considerable amount of research. Aspects
discussed in this document include advances in the
definition of HTN in 16 year or older, clinical significance
of isolated systolic HTN in youth, the importance of out of
office and central blood pressure measurement, new risk
factors for HTN, methods to assess vascular phenotypes,
clustering of cardiovascular risk factors and treatment
strategies among others. The recommendations of the
present document synthesize a considerable amount of
scientific data and clinical experience and represent the
best clinical wisdom upon which physicians, nurses and
families should base their decisions. In addition, as they
call attention to the burden of HTN in children and
adolescents, and its contribution to the current epidemic
of cardiovascular disease, these guidelines should
encourage public policy makers to develop a global effort
to improve identification and treatment of high blood
pressure among children and adolescents.
Keywords:adolescents, central blood pressure, children,
European, management of high blood pressure, out of
office blood pressure, recommendations, society of
hypertension
Abbreviations:ABPM, ambulatory blood pressure
measurement; ACE, angiotensin-converting enzyme; ACEi,
angiotensin-converting enzyme inhibitor; ACTH,
adeenocorticotropic hormone; ARB, AT1 b
2016ESC儿童高血压指南.pdf